Example of Array Tomography in a zebrafish embryo. The sample comprised 12 pieces of tape with 20 sections per tape. A 40 µm x 40 µm x 20 µm volume was recorded at a resolution of 5 x 5 x 80 nm in the aorta region of the 48h PF embryo.
Pharmaceutical and Biotechnology applications
Images of an anti-asthmatic drug deposited from a compressed-gas delivery inhaler onto a TEM grid. In the left image at low magnification, you can see the particles deposited on the surface. The second is a close-up of the particles at a higher magnification showing fine surface details. Taken using the immersion lens at 1 kV accelerating voltage with the in-lens backscatter detector (T1), without metal coating. This shows how high contrast and surface detail can be obtained without complex sample preparation on low-atomic-weight materials using the Trinity and Immersion modes.
Example of microorganisms imaged using the retractable STEM detector, allowing for better contrast and resolution in life science samples.