| Week | Date | Topics | Chapters | Remarks |
|---|---|---|---|---|
| 1 | Aug 24, 26 | Introduction: A survey of Biotechnology-from historical to current | ||
| 2 | Aug 31, Sep 2 | A textbook case of success: Genetech | Lab Exercise: Each student identifies a specific product/biotech company and do a web-based research | |
| 3 | Sep 7, 9 | Review on molecules of life and principles of biological processes, etc. | Class discussion: students present their research | |
| 4 | Sep 14, 16 | Continue on basic biochemistry | Sep 16: 1st Exam | |
| 5 | Sep 21, 23 | Principles of restriction endonuclease and ligase, electrophoresis, and other techniques commonly used in biotechnology | Lab 1: Laboratory Safety; Preparation of buffers, reagents, etc.; | |
| 6 | Sep 28, 30 | Continue...... | Lab 2: Biotech in action: How human accidentally produced wine/alcohol | |
| 7 | Oct 5, 7 | Expression vector and construction | Continue... | |
| 8 | Oct 12, 14 | Genomic libraries vs. cDNA libraries | Oct 14: 2nd Exam | |
| 9 | Oct 19, 21 | Continue...... | Lab 3: DNA gel electrophoresis | |
| 10 | Oct 26, 28 | PCR to gene editing | Oct 26, 27: No class (Fall Break) Lab 4: Plasmid DNA transformation | |
| 11 | Nov 2, 4 | Continue and catch-up | Lab 5: Colony isolation and plasmid DNA Extraction | |
| 12 | Nov 9, 11 | Intellectual property, venture capital, and IPO | Lab 6: “Scale up” of plasmid-positive colony | |
| 13 | Nov 16, 18 | --Continue and catch-up | Nov 18: 3rd Exam | |
| 14 | Nov 23, 25 | A survey of career prospects in biotechnology by logging on companies' job sites, resume preparation, mock interview, etc. | Nov 25-28: Thanksgiving Break Lab 7: “Scale up” plasmid DNA extraction, restriction endonuclease digestion and DNA electrophoresis | |
| 15 | Nov 30, Dec 2 | Catch-up, review, and discussion on issues/student’s lab results | Catch-up and repeat experiments if needed | |
| 16 | Dec 7, 9 | Open / Student project presentation | ||
| 17 | Final Exam |
*The instructor reserves the right to make changes to (delete, add, or modify) this Syllabus as the semester progresses.**Any changes will be announced in class and/or posted on Blackboard.
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