US 41 is a 4-lane divided roadway from William Street to Carmalita Street that transitions to one-way pairs with three travel lanes north of Carmalita Street. North of Harborside Avenue, the left lane transitions to a left turn only lane to the Harborside Yacht Club and Four Points by Sheraton entrance. From there, the road continues on with two lanes until it reaches the Peace River Bridge.

The current configuration requires drivers to change lanes in order to drive through Downtown Punta Gorda.

There are sidewalks included on both sides of Tamiami Trail throughout the project limits, however, there are no bike lanes for the majority of the corridor.