Everyone now has the option to start oral PrEP using a double dose (two pills) for the first dose BEFORE sex. This gives protection within two hours.
Daily dosing then involves continuing with a single pill every day at roughly the same time.
For daily PrEP, current guidelines recommend at least six daily doses a week. Although studies suggest fewer weekly doses might be okay, it is not yet clear if this will be included in the 2024 guidelines update.
But if you stop PrEP for a week, please restart using a double dose and take seven daily post-sex doses that week.
If you are using event-based dosing, continue daily dosing for either another two days (2:1:1 dosing) or seven days (2:7 dosing). See pages 17 to 20.
Before stopping daily dosing, please continue for either two or seven days after you last had sex. This depends on how you are dosing PrEP. See p16 and 17.
TAF/FTC can be dosed the same way as TD/FTC. Although there is less data on vaginal and neovaginal sex this should still be okay.