{ "document_id": 13701, "page": 31, "width_pt": 612, "height_pt": 792, "rotation": 0, "pipeline_version": "paddleocr-vl-1.6+paul-48", "engine": "paddleocr_vl", "source_run_id": 13812, "item_count": 113, "counts_by_type": { "formula": 20, "header": 3, "heading": 1, "table": 1, "table_cell": 24, "text": 64 }, "build_ms": 14, "items": [ { "id": "p31.1", "order": 1, "type": "header", "bbox": { "l": 53.52, "t": 765.84, "r": 70.56, "b": 756.96 }, "text": "534", "attrs": { "block_label": "number" }, "level": 2 }, { "id": "p31.2", "order": 2, "type": "header", "bbox": { "l": 75.6, "t": 766.08, "r": 264.24, "b": 756.24 }, "text": "Journal of Natural Products, 1999, Vol. 62, No. 3", "attrs": { "block_label": "header" }, "level": 2 }, { "id": "p31.3", "order": 3, "type": "header", "bbox": { "l": 501.36, "t": 766.08, "r": 559.68, "b": 756 }, "text": "Invited Review", "attrs": { "block_label": "header" }, "level": 2 }, { "id": "p31.4", "order": 4, "type": "heading", "bbox": { "l": 53.52, "t": 746.16, "r": 142.8, "b": 736.32 }, "text": "Table 4. (Continued)", "attrs": { "block_label": "paragraph_title" }, "level": 3 }, { "id": "p31.5", "order": 5, "type": "text", "bbox": { "l": 224.16, "t": 732.96, "r": 386.88, "b": 723.6 }, "text": "Adjacent Bis-THF Acetogenins (Continued)" }, { "id": "p31.6", "order": 6, "type": "text", "bbox": { "l": 75.6, "t": 722.64, "r": 239.52, "b": 712.56 }, "text": "110. membrarollin[p31.6.1] (C [p31.6.2]H [p31.6.3]O[p31.6.4] MW578)", "children": [ { "id": "p31.6.1", "order": 7, "type": "formula", "bbox": { "l": 75.6, "t": 722.64, "r": 239.52, "b": 712.56 }, "text": "¹³⁷", "attrs": { "latex": "^{137}", "inline": true, "text_offset": 17, "text_span": 9, "bbox_estimated": true, "alt": "to the power of 137", "mathml": "137" } }, { "id": "p31.6.2", "order": 8, "type": "formula", "bbox": { "l": 75.6, "t": 722.64, "r": 239.52, "b": 712.56 }, "text": "₃₅", "attrs": { "latex": "_{35}", "inline": true, "text_offset": 30, "text_span": 9, "bbox_estimated": true, "alt": "sub 35", "mathml": "35" } }, { "id": "p31.6.3", "order": 9, "type": "text", "bbox": { "l": 75.6, "t": 722.64, "r": 239.52, "b": 712.56 }, "text": "₆₂", "attrs": { "inline": true, "text_offset": 41, "text_span": 9, "bbox_estimated": true } }, { "id": "p31.6.4", "order": 10, "type": "formula", "bbox": { "l": 75.6, "t": 722.64, "r": 239.52, "b": 712.56 }, "text": "₆", "attrs": { "latex": "_{6}", "inline": true, "text_offset": 51, "text_span": 9, "bbox_estimated": true, "alt": "sub 6", "mathml": "6" } } ] }, { "id": "p31.7", "order": 11, "type": "formula", "bbox": { "l": 159.6, "t": 708.96, "r": 453.36, "b": 662.4 }, "text": "", "attrs": { "block_label": "image", "alt": "Skeletal structure of an annonaceous acetogenin: bis-tetrahydrofuran core with two hydroxyls, long alkyl chain, and a buteno…", "source": "vision" } }, { "id": "p31.8", "order": 12, "type": "text", "bbox": { "l": 158.64, "t": 653.04, "r": 387.36, "b": 643.44 }, "text": "Position 13 14 17 18 21 22" }, { "id": "p31.9", "order": 13, "type": "text", "bbox": { "l": 158.16, "t": 641.04, "r": 391.92, "b": 617.52 }, "text": "[p31.9.1]H (δ) 3.40 dt 3.81 m 3.87 m 3.87 m 3.90 m 3.85 m\n [p31.9.2]C (δ) 74.00 83.02 81.10 80.99 83.02 71.91", "children": [ { "id": "p31.9.1", "order": 14, "type": "formula", "bbox": { "l": 158.16, "t": 641.04, "r": 391.92, "b": 617.52 }, "text": "¹", "attrs": { "latex": "^{1}", "inline": true, "text_offset": 0, "text_span": 9, "bbox_estimated": true, "alt": "to the power of 1", "mathml": "1" } }, { "id": "p31.9.2", "order": 15, "type": "text", "bbox": { "l": 158.16, "t": 641.04, "r": 391.92, "b": 617.52 }, "text": "¹³", "attrs": { "inline": true, "text_offset": 59, "text_span": 9, "bbox_estimated": true } } ] }, { "id": "p31.10", "order": 16, "type": "text", "bbox": { "l": 77.28, "t": 615.84, "r": 534.24, "b": 574.32 }, "text": "White wax. [α]D: +10° (c O.8, MeOH). UV (λmax, MeOH, nm): 210 (log ε 3.95). IR (νmax, film, cm⁻¹): 3370, 2940, 2880, 1750, 1456, 1380, 1039. MS: EIMS m/z 578, 560, 542, 436, 407, 390, 337, 319, 311, 267, 241, 223, 171, 153, 111, 97. NMR: ¹H NMR (400MHz, CDCl₃), ¹³C NMR (100MHz, CDCl₃). Derivatives: per-MTPA esters (¹H NMR), p-bromophenylurethane (¹H NMR). Biological activities: NADH oxidase IC₅₀O.3nM. Source: Rollinia membranacea, seeds." }, { "id": "p31.11", "order": 17, "type": "text", "bbox": { "l": 77.04, "t": 579.36, "r": 231.84, "b": 568.56 }, "text": "111. guanaconne[p31.11.1] (C [p31.11.2]H [p31.11.3]O[p31.11.4] MW620)", "children": [ { "id": "p31.11.1", "order": 18, "type": "formula", "bbox": { "l": 77.04, "t": 579.36, "r": 231.84, "b": 568.56 }, "text": "¹³⁸", "attrs": { "latex": "^{138}", "inline": true, "text_offset": 15, "text_span": 10, "bbox_estimated": true, "alt": "to the power of 138", "mathml": "138" } }, { "id": "p31.11.2", "order": 19, "type": "text", "bbox": { "l": 77.04, "t": 579.36, "r": 231.84, "b": 568.56 }, "text": "₃₇", "attrs": { "inline": true, "text_offset": 29, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.11.3", "order": 20, "type": "text", "bbox": { "l": 77.04, "t": 579.36, "r": 231.84, "b": 568.56 }, "text": "₆₄", "attrs": { "inline": true, "text_offset": 41, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.11.4", "order": 21, "type": "text", "bbox": { "l": 77.04, "t": 579.36, "r": 231.84, "b": 568.56 }, "text": "₇", "attrs": { "inline": true, "text_offset": 52, "text_span": 10, "bbox_estimated": true } } ] }, { "id": "p31.12", "order": 22, "type": "formula", "bbox": { "l": 154.32, "t": 563.52, "r": 458.4, "b": 519.84 }, "text": "", "attrs": { "block_label": "image", "alt": "Skeletal structure of an annonaceous acetogenin-type bis-tetrahydrofuran butenolide with hydroxyl groups at C-15 and C-24 an…", "source": "vision" } }, { "id": "p31.13", "order": 23, "type": "text", "bbox": { "l": 153.6, "t": 512.64, "r": 417.84, "b": 503.04 }, "text": "Position 10 15 16 19 20 23 24" }, { "id": "p31.14", "order": 24, "type": "text", "bbox": { "l": 153.36, "t": 499.92, "r": 421.2, "b": 476.64 }, "text": "[p31.14.1]H (δ) - 3.39 m 3.78 m 3.92 m 3.78 m 3.78 m 3.84 m\n [p31.14.2]C (δ) 211.46 73.86 83.23 82.50 82.25 82.79 71.19", "children": [ { "id": "p31.14.1", "order": 25, "type": "text", "bbox": { "l": 153.36, "t": 499.92, "r": 421.2, "b": 476.64 }, "text": "¹", "attrs": { "inline": true, "text_offset": 0, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.14.2", "order": 26, "type": "text", "bbox": { "l": 153.36, "t": 499.92, "r": 421.2, "b": 476.64 }, "text": "¹³", "attrs": { "inline": true, "text_offset": 61, "text_span": 10, "bbox_estimated": true } } ] }, { "id": "p31.15", "order": 27, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "Colorless wax.[p31.15.1]: +22° (c 1, EtOH). UV ([p31.15.2], MeOH, nm): 208 (log[p31.15.3] 3.83). IR ([p31.15.4], film, cm[p31.15.5]): 3416, 2922, 1751, 1647, 1548, 1066 MS: EIMS m/z 449, 379, 361, 311, 309, 293, 291, 241, 223, 195. NMR: [p31.15.6]H NMR (400MHz, CDCl[p31.15.7]), [p31.15.8]C NMR (100MHz, CDCl[p31.15.9]). Derivatives: per-MTPA esters ( [p31.15.10]H NMR). Biological activities: NADH oxidase IC [p31.15.11]", "children": [ { "id": "p31.15.1", "order": 28, "type": "formula", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "[\\alpha]_{D}", "attrs": { "latex": "[\\alpha]_{D}", "inline": true, "text_offset": 14, "text_span": 10, "bbox_estimated": true, "notation": "latex", "alt": "alpha sub D", "mathml": "[α]D" } }, { "id": "p31.15.2", "order": 29, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "\\lambda_{max}", "attrs": { "inline": true, "text_offset": 48, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.15.3", "order": 30, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "ε", "attrs": { "inline": true, "text_offset": 79, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.15.4", "order": 31, "type": "formula", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "\\nu_{max}\\ \\text{(partial: IR label; the visible text is a chemistry paper's characterization paragraph, which includes } [\\alpha]_D: +22^\\circ (c\\ 1, \\text{EtOH}) \\text{, UV } (\\lambda_{max}, \\text{MeOH, nm}): 208 (\\log \\epsilon\\ 3.83)\\text{, IR } (\\nu_{max}, \\text{film, cm}^{-1}): 3416, 2922, 1751, 1647, 1548, 1066\\text{, MS: EIMS } m/z\\ 449, 379, 361, 311, 309, 293, 291, 241, 223, 195\\text{, NMR: }{}^{1}\\text{H NMR (400 MHz, CDCl}_3\\text{), }{}^{13}\\text{C NMR (100 MHz, CDCl}_3\\text{). Derivatives: per-MTPA esters } ({}^{1}\\text{H NMR}).\\text{ Biological activities: NADH oxidase } IC_{50}\\ 1.5\\,\\text{nM. Source: } \\textit{Annona sprague}i\\text{, seeds.)}", "attrs": { "latex": "\\nu_{max}\\ \\text{(partial: IR label; the visible text is a chemistry paper's characterization paragraph, which includes } [\\alpha]_D: +22^\\circ (c\\ 1, \\text{EtOH}) \\text{, UV } (\\lambda_{max}, \\text{MeOH, nm}): 208 (\\log \\epsilon\\ 3.83)\\text{, IR } (\\nu_{max}, \\text{film, cm}^{-1}): 3416, 2922, 1751, 1647, 1548, 1066\\text{, MS: EIMS } m/z\\ 449, 379, 361, 311, 309, 293, 291, 241, 223, 195\\text{, NMR: }{}^{1}\\text{H NMR (400 MHz, CDCl}_3\\text{), }{}^{13}\\text{C NMR (100 MHz, CDCl}_3\\text{). Derivatives: per-MTPA esters } ({}^{1}\\text{H NMR}).\\text{ Biological activities: NADH oxidase } IC_{50}\\ 1.5\\,\\text{nM. Source: } \\textit{Annona sprague}i\\text{, seeds.)}", "inline": true, "text_offset": 101, "text_span": 10, "bbox_estimated": true, "notation": "latex", "alt": "nu sub max of partial: IR label; the visible text is a chemistry paper's characterization paragraph, which includes alpha sub D : plus 22 to the power of circ of c 1, EtOH, UV of lambda sub max, MeOH, nm : 208 times log epsilon 3.83, IR of nu sub max, film, cm to the power of minus 1 : 3416, 2922, 1751, 1647, 1548, 1066, MS: EIMS m over z 449, 379, 361, 311, 309, 293, 291, 241, 223, 195, NMR: to the power of 1 H NMR of 400 MHz, CDCl sub 3, to the power of 13 C NMR of 100 MHz, CDCl sub 3 . Derivatives: per minus MTPA esters of to the power of 1 H NMR . Biological activities: NADH oxidase IC sub 50 1.5, nM. Source: textit Annona sprague i, seeds.", "mathml": "νmax (partial: IR label; the visible text is a chemistry paper's characterization paragraph, which includes [α]D:+22∘(c 1,EtOH), UV (λmax,MeOH, nm):208(logϵ 3.83), IR (νmax,film, cm−1):3416,2922,1751,1647,1548,1066, MS: EIMS m/z 449,379,361,311,309,293,291,241,223,195, NMR: 1H NMR (400 MHz, CDCl3), 13C NMR (100 MHz, CDCl3). Derivatives: per-MTPA esters (1H NMR). Biological activities: NADH oxidase IC50 1.5nM. Source: Annona spraguei, seeds.)" } }, { "id": "p31.15.5", "order": 32, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "⁻¹", "attrs": { "inline": true, "text_offset": 121, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.15.6", "order": 33, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "¹", "attrs": { "inline": true, "text_offset": 237, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.15.7", "order": 34, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "₃", "attrs": { "inline": true, "text_offset": 266, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.15.8", "order": 35, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "¹³", "attrs": { "inline": true, "text_offset": 279, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.15.9", "order": 36, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "₃", "attrs": { "inline": true, "text_offset": 308, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.15.10", "order": 37, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "¹", "attrs": { "inline": true, "text_offset": 352, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.15.11", "order": 38, "type": "text", "bbox": { "l": 77.04, "t": 476.64, "r": 533.04, "b": 442.8 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 410, "text_span": 11, "bbox_estimated": true } } ] }, { "id": "p31.16", "order": 39, "type": "text", "bbox": { "l": 86.16, "t": 447.36, "r": 239.28, "b": 438.96 }, "text": "1.5nM Source: Annona spraguei, seeds." }, { "id": "p31.17", "order": 40, "type": "text", "bbox": { "l": 240.48, "t": 434.4, "r": 371.52, "b": 424.32 }, "text": "Nonadjacent Bis-THF Acetogenins" }, { "id": "p31.18", "order": 41, "type": "text", "bbox": { "l": 75.84, "t": 424.08, "r": 235.92, "b": 414 }, "text": "112. goniotriocin[p31.18.1] (C [p31.18.2]H [p31.18.3]O[p31.18.4], MW636)", "children": [ { "id": "p31.18.1", "order": 42, "type": "text", "bbox": { "l": 75.84, "t": 424.08, "r": 235.92, "b": 414 }, "text": "^{*39}", "attrs": { "inline": true, "text_offset": 17, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.18.2", "order": 43, "type": "text", "bbox": { "l": 75.84, "t": 424.08, "r": 235.92, "b": 414 }, "text": "₃₇", "attrs": { "inline": true, "text_offset": 31, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.18.3", "order": 44, "type": "formula", "bbox": { "l": 75.84, "t": 424.08, "r": 235.92, "b": 414 }, "text": "₆₅", "attrs": { "latex": "_{65}", "inline": true, "text_offset": 43, "text_span": 10, "bbox_estimated": true, "alt": "sub 65", "mathml": "65" } }, { "id": "p31.18.4", "order": 45, "type": "text", "bbox": { "l": 75.84, "t": 424.08, "r": 235.92, "b": 414 }, "text": "₈", "attrs": { "inline": true, "text_offset": 54, "text_span": 10, "bbox_estimated": true } } ] }, { "id": "p31.19", "order": 46, "type": "formula", "bbox": { "l": 155.76, "t": 412.32, "r": 456.96, "b": 364.8 }, "text": "", "attrs": { "block_label": "image", "alt": "Skeletal structure of an annonaceous acetogenin: butenolide, two tetrahydrofuran rings, hydroxyls at C4, C14, C17, and a C22…", "source": "vision" } }, { "id": "p31.20", "order": 47, "type": "text", "bbox": { "l": 155.28, "t": 355.44, "r": 382.56, "b": 346.08 }, "text": "Position 10 13 14 17 20 22" }, { "id": "p31.21", "order": 48, "type": "text", "bbox": { "l": 155.04, "t": 342.48, "r": 356.88, "b": 332.88 }, "text": "[p31.21.1]H (δ) 3.88 m 3.75 q 3.41 dt 3.80 dt 4.62 ddd", "children": [ { "id": "p31.21.1", "order": 49, "type": "formula", "bbox": { "l": 155.04, "t": 342.48, "r": 356.88, "b": 332.88 }, "text": "¹", "attrs": { "latex": "^{1}", "inline": true, "text_offset": 0, "text_span": 10, "bbox_estimated": true, "alt": "to the power of 1", "mathml": "1" } } ] }, { "id": "p31.22", "order": 50, "type": "text", "bbox": { "l": 154.8, "t": 330.72, "r": 386.88, "b": 320.4 }, "text": "[p31.22.1]C ([p31.22.2]) 79.3 81.9 74.7 82.7 73.4 209.6", "children": [ { "id": "p31.22.1", "order": 51, "type": "text", "bbox": { "l": 154.8, "t": 330.72, "r": 386.88, "b": 320.4 }, "text": "¹³", "attrs": { "inline": true, "text_offset": 0, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.22.2", "order": 52, "type": "formula", "bbox": { "l": 154.8, "t": 330.72, "r": 386.88, "b": 320.4 }, "text": "δ", "attrs": { "latex": "\\delta", "inline": true, "text_offset": 13, "text_span": 10, "bbox_estimated": true, "alt": "delta", "mathml": "δ" } } ] }, { "id": "p31.23", "order": 53, "type": "text", "bbox": { "l": 77.52, "t": 318, "r": 519.6, "b": 268.08 }, "text": "White wax. [α]D: +10.0° (c 0.03, CHCl₃). IR (νmax, film, cm⁻¹): 3378, 2925, 2853, 1750, 1718, 1458, 1066. MS: CIMS (isobutane) m/z 637, 619, 601, 583. EIMS m/z 425, 407, 389, 381, 371, 363, 345, 339, 337, 321, 281, 263, 245, 197, 141. NMR: ¹H NMR (500 MHz, CDCl₃), ¹³C NMR (125 MHz, CDCl₃). Derivatives: per-MTPA esters (¹H NMR). Biological activities (μg/mL): BST LC₅₀ 27, A-549 ED₅₀ 3.3 × 10⁻², MCF-7 ED₅₀ 3.3 × 10⁻⁵, HT-29 ED₅₀ 1.2 × 10⁻³, A-498 ED₅₀ 1.1, PC-3 ED₅₀ 2.6 × 10⁻¹, PACA-2 ED₅₀ 1.4. Source: Goniothalamus giganteus, stem bark." }, { "id": "p31.24", "order": 54, "type": "text", "bbox": { "l": 77.76, "t": 272.64, "r": 234.72, "b": 261.6 }, "text": "113. trilobalicin[p31.24.1] (C [p31.24.2]H [p31.24.3]O[p31.24.4], MW610)", "children": [ { "id": "p31.24.1", "order": 55, "type": "formula", "bbox": { "l": 77.76, "t": 272.64, "r": 234.72, "b": 261.6 }, "text": "^{*119}", "attrs": { "latex": "^{*119}", "inline": true, "text_offset": 17, "text_span": 10, "bbox_estimated": true, "notation": "latex", "alt": "to the power of *119", "mathml": "*119" } }, { "id": "p31.24.2", "order": 56, "type": "formula", "bbox": { "l": 77.76, "t": 272.64, "r": 234.72, "b": 261.6 }, "text": "₃₅", "attrs": { "latex": "_{35}", "inline": true, "text_offset": 31, "text_span": 10, "bbox_estimated": true, "alt": "sub 35", "mathml": "35" } }, { "id": "p31.24.3", "order": 57, "type": "text", "bbox": { "l": 77.76, "t": 272.64, "r": 234.72, "b": 261.6 }, "text": "₆₂", "attrs": { "inline": true, "text_offset": 43, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.24.4", "order": 58, "type": "formula", "bbox": { "l": 77.76, "t": 272.64, "r": 234.72, "b": 261.6 }, "text": "₈", "attrs": { "latex": "_{8}", "inline": true, "text_offset": 54, "text_span": 10, "bbox_estimated": true, "alt": "sub 8", "mathml": "8" } } ] }, { "id": "p31.25", "order": 59, "type": "formula", "bbox": { "l": 160.32, "t": 255.36, "r": 452.16, "b": 213.12 }, "text": "", "attrs": { "block_label": "image", "alt": "Skeletal structure of an annonaceous acetogenin-type bis-THF compound with a butenolide terminus, hydroxyls at C4, C14, C17,…", "source": "vision" } }, { "id": "p31.26", "order": 60, "type": "table", "bbox": { "l": 158.64, "t": 202.8, "r": 427.92, "b": 167.04 }, "text": "", "attrs": { "block_label": "table", "n_rows": 3, "n_cols": 8, "integrity": { "skipped": "no_text_layer" } }, "children": [ { "id": "p31.26.1", "order": 61, "type": "table_cell", "bbox": { "l": 158.64, "t": 202.8, "r": 192.3, "b": 190.88 }, "text": "Position", "attrs": { "row": 0, "col": 0, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.2", "order": 62, "type": "table_cell", "bbox": { "l": 192.3, "t": 202.8, "r": 225.96, "b": 190.88 }, "text": "10", "attrs": { "row": 0, "col": 1, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.3", "order": 63, "type": "table_cell", "bbox": { "l": 225.96, "t": 202.8, "r": 259.62, "b": 190.88 }, "text": "13", "attrs": { "row": 0, "col": 2, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.4", "order": 64, "type": "table_cell", "bbox": { "l": 259.62, "t": 202.8, "r": 293.28, "b": 190.88 }, "text": "14", "attrs": { "row": 0, "col": 3, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.5", "order": 65, "type": "table_cell", "bbox": { "l": 293.28, "t": 202.8, "r": 326.94, "b": 190.88 }, "text": "17", "attrs": { "row": 0, "col": 4, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.6", "order": 66, "type": "table_cell", "bbox": { "l": 326.94, "t": 202.8, "r": 360.6, "b": 190.88 }, "text": "18", "attrs": { "row": 0, "col": 5, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.7", "order": 67, "type": "table_cell", "bbox": { "l": 360.6, "t": 202.8, "r": 394.26, "b": 190.88 }, "text": "21", "attrs": { "row": 0, "col": 6, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.8", "order": 68, "type": "table_cell", "bbox": { "l": 394.26, "t": 202.8, "r": 427.92, "b": 190.88 }, "text": "22", "attrs": { "row": 0, "col": 7, "rowspan": 1, "colspan": 1, "column_header": true, "header_source": "heuristic" } }, { "id": "p31.26.9", "order": 69, "type": "table_cell", "bbox": { "l": 158.64, "t": 190.88, "r": 192.3, "b": 178.96 }, "text": "¹H ( δ)", "attrs": { "row": 1, "col": 0, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.10", "order": 70, "type": "table_cell", "bbox": { "l": 192.3, "t": 190.88, "r": 225.96, "b": 178.96 }, "text": "3.87 m", "attrs": { "row": 1, "col": 1, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.11", "order": 71, "type": "table_cell", "bbox": { "l": 225.96, "t": 190.88, "r": 259.62, "b": 178.96 }, "text": "3.80 m", "attrs": { "row": 1, "col": 2, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.12", "order": 72, "type": "table_cell", "bbox": { "l": 259.62, "t": 190.88, "r": 293.28, "b": 178.96 }, "text": "3.41 m", "attrs": { "row": 1, "col": 3, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.13", "order": 73, "type": "table_cell", "bbox": { "l": 293.28, "t": 190.88, "r": 326.94, "b": 178.96 }, "text": "3.41 m", "attrs": { "row": 1, "col": 4, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.14", "order": 74, "type": "table_cell", "bbox": { "l": 326.94, "t": 190.88, "r": 360.6, "b": 178.96 }, "text": "3.86 m", "attrs": { "row": 1, "col": 5, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.15", "order": 75, "type": "table_cell", "bbox": { "l": 360.6, "t": 190.88, "r": 394.26, "b": 178.96 }, "text": "3.87 m", "attrs": { "row": 1, "col": 6, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.16", "order": 76, "type": "table_cell", "bbox": { "l": 394.26, "t": 190.88, "r": 427.92, "b": 178.96 }, "text": "3.80 m", "attrs": { "row": 1, "col": 7, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.17", "order": 77, "type": "table_cell", "bbox": { "l": 158.64, "t": 178.96, "r": 192.3, "b": 167.04 }, "text": "¹³C ( δ)", "attrs": { "row": 2, "col": 0, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.18", "order": 78, "type": "table_cell", "bbox": { "l": 192.3, "t": 178.96, "r": 225.96, "b": 167.04 }, "text": "79.3", "attrs": { "row": 2, "col": 1, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.19", "order": 79, "type": "table_cell", "bbox": { "l": 225.96, "t": 178.96, "r": 259.62, "b": 167.04 }, "text": "82.0", "attrs": { "row": 2, "col": 2, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.20", "order": 80, "type": "table_cell", "bbox": { "l": 259.62, "t": 178.96, "r": 293.28, "b": 167.04 }, "text": "74.4", "attrs": { "row": 2, "col": 3, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.21", "order": 81, "type": "table_cell", "bbox": { "l": 293.28, "t": 178.96, "r": 326.94, "b": 167.04 }, "text": "74.6", "attrs": { "row": 2, "col": 4, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.22", "order": 82, "type": "table_cell", "bbox": { "l": 326.94, "t": 178.96, "r": 360.6, "b": 167.04 }, "text": "83.3", "attrs": { "row": 2, "col": 5, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.23", "order": 83, "type": "table_cell", "bbox": { "l": 360.6, "t": 178.96, "r": 394.26, "b": 167.04 }, "text": "82.2", "attrs": { "row": 2, "col": 6, "rowspan": 1, "colspan": 1 } }, { "id": "p31.26.24", "order": 84, "type": "table_cell", "bbox": { "l": 394.26, "t": 178.96, "r": 427.92, "b": 167.04 }, "text": "71.6", "attrs": { "row": 2, "col": 7, "rowspan": 1, "colspan": 1 } } ] }, { "id": "p31.27", "order": 85, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "White wax.[p31.27.1]: +13.6° (c 0.125, CHCl_{3}). IR ([p31.27.2], film, cm^{-1}): 3333, 2919, 2866, 1738, 1594, 1456, 1398, 1116 MS: EIMS m/z 585, 545, 495, 455, 405, 365, 353, 313, 275, 263, 223, 213, NMR: [p31.27.3]H NMR (500 MHz, CDCl_{3}), [p31.27.4]C NMR (125 MHz, CDCl_{3}). Derivatives: per-MTPA esters ( [p31.27.5]H NMR), TMS (EIMS). Biological activities ( [p31.27.6]g/mL): BST LC[p31.27.7] 5.8, A-549 ED[p31.27.8] 5.8[p31.27.9] 10[p31.27.10], MCF-7 ED[p31.27.11] 1.6[p31.27.12] 10[p31.27.13], HT-29 ED[p31.27.14] 2.3, A-498 ED[p31.27.15] 6.0[p31.27.16] 10[p31.27.17], PC-3 ED[p31.27.18] 9.8[p31.27.19] 10[p31.27.20], PAC-2 ED[p31.27.21] 2.8[p31.27.22] 10[p31.27.23]. Source: Asimina triloba, stem bark.", "children": [ { "id": "p31.27.1", "order": 86, "type": "formula", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "[\\alpha]_{D}", "attrs": { "latex": "[\\alpha]_{D}", "inline": true, "text_offset": 10, "text_span": 10, "bbox_estimated": true, "notation": "latex", "alt": "alpha sub D", "mathml": "[α]D" } }, { "id": "p31.27.2", "order": 87, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "\\nu_{max}", "attrs": { "inline": true, "text_offset": 54, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.3", "order": 88, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "¹", "attrs": { "inline": true, "text_offset": 207, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.4", "order": 89, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "¹³", "attrs": { "inline": true, "text_offset": 244, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.5", "order": 90, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "¹", "attrs": { "inline": true, "text_offset": 312, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.6", "order": 91, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "μ", "attrs": { "inline": true, "text_offset": 366, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.7", "order": 92, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 389, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.8", "order": 93, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 413, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.9", "order": 94, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "×", "attrs": { "inline": true, "text_offset": 427, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.27.10", "order": 95, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "⁻⁸", "attrs": { "inline": true, "text_offset": 440, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.11", "order": 96, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 461, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.12", "order": 97, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "×", "attrs": { "inline": true, "text_offset": 476, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.13", "order": 98, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "⁻⁷", "attrs": { "inline": true, "text_offset": 490, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.14", "order": 99, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 511, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.15", "order": 100, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 536, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.16", "order": 101, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "×", "attrs": { "inline": true, "text_offset": 551, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.17", "order": 102, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "⁻³", "attrs": { "inline": true, "text_offset": 565, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.18", "order": 103, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 585, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.19", "order": 104, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "×", "attrs": { "inline": true, "text_offset": 600, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.20", "order": 105, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "⁻¹", "attrs": { "inline": true, "text_offset": 614, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.21", "order": 106, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "₅₀", "attrs": { "inline": true, "text_offset": 635, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.22", "order": 107, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "×", "attrs": { "inline": true, "text_offset": 650, "text_span": 11, "bbox_estimated": true } }, { "id": "p31.27.23", "order": 108, "type": "text", "bbox": { "l": 78.96, "t": 165.12, "r": 532.56, "b": 120.96 }, "text": "⁻¹", "attrs": { "inline": true, "text_offset": 664, "text_span": 11, "bbox_estimated": true } } ] }, { "id": "p31.28", "order": 109, "type": "text", "bbox": { "l": 76.56, "t": 119.52, "r": 364.08, "b": 109.44 }, "text": "gigantecinone[p31.28.1] (reported as a cis and trans mixture) ([p31.28.2], MW638)", "children": [ { "id": "p31.28.1", "order": 110, "type": "text", "bbox": { "l": 76.56, "t": 119.52, "r": 364.08, "b": 109.44 }, "text": "¹²⁶", "attrs": { "inline": true, "text_offset": 13, "text_span": 10, "bbox_estimated": true } }, { "id": "p31.28.2", "order": 111, "type": "formula", "bbox": { "l": 76.56, "t": 119.52, "r": 364.08, "b": 109.44 }, "text": "C₃₇H₆₆O₈", "attrs": { "latex": "C_{37}H_{66}O_{8}", "inline": true, "text_offset": 63, "text_span": 10, "bbox_estimated": true, "alt": "C sub 37 H sub 66 O sub 8", "mathml": "C37H66O8" } } ] }, { "id": "p31.29", "order": 112, "type": "text", "bbox": { "l": 400.08, "t": 107.04, "r": 428.16, "b": 99.36 }, "text": "cis/trans" }, { "id": "p31.30", "order": 113, "type": "formula", "bbox": { "l": 154.32, "t": 105.84, "r": 457.2, "b": 61.44 }, "text": "", "attrs": { "block_label": "image", "alt": "Skeletal structure of an acetogenin-type lactone with two tetrahydrofuran rings, hydroxyls at C14, C17, C22, and a ketone at…", "source": "vision" } } ], "excluded_furniture": { "first": [], "last": [] } }